Scipion Web Tools -

Domain-Domain Interaction Analysis

The 'Domain-Domain Interaction Analysis' tool is used to analyze the potential interaction between the domains of a protein complex based on DIMERO scores. In this scenario Scipion Web Tools scores all phisycal interactions between the domains of a protein complex. The figure below dsiplays how this information is organized in a html table. The location of the protein domains and the DIMERO scores are diplayed in the table for all interacting domain pairs, also the 'Struct. Model' column indicates if structural evidence of the DDI is available with a green tick or not with a red corss. The radio button located in the left site of the table can be clicked to map the domains in the protein complex structure.

Figure DDI sstructure analysis.